Longevity is determined by ETS transcription factors in multiple tissues and diverse species.

Longevity is determined by ETS transcription factors in multiple tissues and diverse species.

Ageing populations pose one of the main public health crises of our time. Reprogramming gene expression by altering the activities of sequence-specific transcription factors (TFs) can ameliorate deleterious effects of age. Here we explore how a circuit of TFs coordinates pro-longevity transcriptiona...

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Bibliographic Details
Main Authors: Adam J Dobson, Richard Boulton-McDonald, Lara Houchou, Tatiana Svermova, Ziyu Ren, Jeremie Subrini, Mireya Vazquez-Prada, Mimoza Hoti, Maria Rodriguez-Lopez, Rita Ibrahim, Afroditi Gregoriou, Alexis Gkantiragas, Jürg Bähler, Marina Ezcurra, Nazif Alic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008212

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https://doi.org/10.1371/journal.pgen.1008212

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