The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans.

SARS-CoV-2 genome annotation revealed the presence of 10 open reading frames (ORFs), of which the last one (ORF10) is positioned downstream of the N gene. It is a hypothetical gene, which was speculated to encode a 38 aa protein. This hypothetical protein does not share sequence similarity with any...

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Bibliographic Details
Main Authors: Katarzyna Pancer, Aleksandra Milewska, Katarzyna Owczarek, Agnieszka Dabrowska, Michał Kowalski, Paweł P Łabaj, Wojciech Branicki, Marek Sanak, Krzysztof Pyrc
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008959