Transcranial Focal Electric Stimulation Avoids P-Glycoprotein Over-Expression during Electrical Amygdala Kindling and Delays Epileptogenesis in Rats

Transcranial Focal Electric Stimulation Avoids P-Glycoprotein Over-Expression during Electrical Amygdala Kindling and Delays Epileptogenesis in Rats

Recent evidence suggests that P-glycoprotein (P-gp) overexpression mediates hyperexcitability and is associated with epileptogenesis. Transcranial focal electrical stimulation (TFS) delays epileptogenesis and inhibits P-gp overexpression after a generalized seizure. Here, first we measured P-gp expr...

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Bibliographic Details
Main Authors: Daniel Fonseca-Barriendos, José Luis Castañeda-Cabral, Frida Martínez-Cuevas, Walter Besio, Alejandro Valdés-Cruz, Luisa Rocha
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Life
Subjects:
P-glycoprotein
epileptogenesis
neuromodulation
hippocampus
neocortex
kindling
Online Access:https://www.mdpi.com/2075-1729/13/6/1294

Internet

https://www.mdpi.com/2075-1729/13/6/1294

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