Opposing roles of Fos, Raw, and SARM1 in the regulation of axonal degeneration and synaptic structure

IntroductionThe degeneration of injured axons is driven by conserved molecules, including the sterile armadillo TIR domain-containing protein SARM1, the cJun N-terminal kinase JNK, and regulators of these proteins. These molecules are also implicated in the regulation of synapse development though t...

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Bibliographic Details
Main Authors: Thomas J. Waller, Catherine A. Collins
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1283995/full