Gbdmr: identifying differentially methylated CpG regions in the human genome via generalized beta regressions

Abstract Background DNA methylation is a biochemical process in which a methyl group is added to the cytosine-phosphate-guanine (CpG) site on DNA molecules without altering the DNA sequence. Multiple CpG sites in a certain genome region can be differentially methylated across phenotypes. Identifying...

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Bibliographic Details
Main Authors: Chengzhou Wu, Xichen Mou, Hongmei Zhang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-024-05711-y