Large-Scale Machine Learning Analysis Reveals DNA Methylation and Gene Expression Response Signatures for Gemcitabine-Treated Pancreatic Cancer

Background: Gemcitabine is a first-line chemotherapy for pancreatic adenocarcinoma (PAAD), but many PAAD patients do not respond to gemcitabine-containing treatments. Being able to predict such nonresponders would hence permit the undelayed administration of more promising treatments while sparing g...

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Bibliographic Details
Main Authors: Adeolu Ogunleye, Chayanit Piyawajanusorn, Ghita Ghislat, Pedro J. Ballester
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2024-01-01
Series:Health Data Science
Online Access:https://spj.science.org/doi/10.34133/hds.0108