A Flavonoid Compound Promotes Neuronal Differentiation of Embryonic Stem Cells via PPAR-β Modulating Mitochondrial Energy Metabolism.

Relatively little is known regarding mitochondrial metabolism in neuronal differentiation of embryonic stem (ES) cells. By using a small molecule, present research has investigated the pattern of cellular energy metabolism in neural progenitor cells derived from mouse ES cells. Flavonoid compound 4a...

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Bibliographic Details
Main Authors: Yu-Qin Mei, Zong-Fu Pan, Wen-Teng Chen, Min-Hua Xu, Dan-Yan Zhu, Yong-Ping Yu, Yi-Jia Lou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4912105?pdf=render