Adiponectin Related Vascular and Cardiac Benefits in Obesity: Is There a Role for an Epigenetically Regulated Mechanism?

Adiponectin Related Vascular and Cardiac Benefits in Obesity: Is There a Role for an Epigenetically Regulated Mechanism?

In obesity, several epigenetic modifications, including histones remodeling, DNA methylation, and microRNAs, could accumulate and determine increased expression of inflammatory molecules, the adipokines, that in turn might induce or accelerate the onset and development of cardiovascular and metaboli...

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Bibliographic Details
Main Authors: Rosaria Anna Fontanella, Lucia Scisciola, Maria Rosaria Rizzo, Surina Surina, Celestino Sardu, Raffaele Marfella, Giuseppe Paolisso, Michelangela Barbieri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
adiponectin
obesity
inflammation
epigenetic mechanisms
cardiovascular complications
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.768026/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.768026/full

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