The Relationship between Hydrophobicity and Drug-Protein Binding in Human Serum Albumin: A Quartz Crystal Microbalance Study

The Relationship between Hydrophobicity and Drug-Protein Binding in Human Serum Albumin: A Quartz Crystal Microbalance Study

In this paper, the quartz crystal microbalance with dissipation monitoring (QCM-D) was used to investigate hydrophobicity and binding strength (K<sub>D</sub>) for 10 different drugs interacting with human serum albumin (HSA). Quantitative structure activity relationship (QSAR) analysis w...

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Bibliographic Details
Main Authors: Ahmad R. Alhankawi, Jacob K. Al-Husseini, Archie Spindler, Clark Baker, Tonderai T. Shoniwa, Mohammed Ahmed, Peter A. Chiarelli, Malkiat S. Johal
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biophysica
Subjects:
QCM-D
hydrophobicity
ligand
binding
HSA
BSA
Online Access:https://www.mdpi.com/2673-4125/2/2/12

Internet

https://www.mdpi.com/2673-4125/2/2/12

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