Levels of extracellular matrix metabolites are associated with changes in Ankylosing Spondylitis Disease Activity Score and MRI inflammation scores in patients with axial spondyloarthritis during TNF inhibitor therapy

Levels of extracellular matrix metabolites are associated with changes in Ankylosing Spondylitis Disease Activity Score and MRI inflammation scores in patients with axial spondyloarthritis during TNF inhibitor therapy

Abstract Background/purpose In axial spondyloarthritis (axSpA) inflammation of the sacroiliac joints and spine is associated with local extracellular matrix (ECM) remodeling of affected tissues. We aimed to investigate the association of ECM metabolites with treatment response in axSpA patients trea...

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Bibliographic Details
Main Authors: Signe Holm Nielsen, Shu Sun, Anne C. Bay-Jensen, Morten Karsdal, Inge Juul Sørensen, Ulrich Weber, Anne Gitte Loft, Gina Kollerup, Gorm Thamsborg, Ole Rintek Madsen, Jakob Møller, Mikkel Østergaard, Susanne Juhl Pedersen
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Arthritis Research & Therapy
Online Access:https://doi.org/10.1186/s13075-022-02967-8

Internet

https://doi.org/10.1186/s13075-022-02967-8

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