Domain IV of Annexin A5 Is Critical for Binding Calcium and Guarantees Its Maximum Binding to the Phosphatidylserine Membrane

Domain IV of Annexin A5 Is Critical for Binding Calcium and Guarantees Its Maximum Binding to the Phosphatidylserine Membrane

Background: Although domain IV of annexin A5 (anxA5) may be less effective in binding phosphatidylserine (PS), the four domains together may guarantee the maximum binding of anxA5 to the PS membrane. Additionally, previous research has shown that annexin mutants lacking one or more domain(s) have di...

Full description

Bibliographic Details
Main Authors: Jie Wang, Jing Liu, Yulu Cao, Minjin Hu, Zichun Hua
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
annexin A5
domain IV
calcium
phosphatidylserine
binding
Online Access:https://www.mdpi.com/1420-3049/22/12/2256

Internet

https://www.mdpi.com/1420-3049/22/12/2256

Similar Items