Dexamethasone-Induced Adipose Tissue Redistribution and Metabolic Changes: Is Gene Expression the Main Factor? An Animal Model of Chronic Hypercortisolism

Dexamethasone-Induced Adipose Tissue Redistribution and Metabolic Changes: Is Gene Expression the Main Factor? An Animal Model of Chronic Hypercortisolism

Chronic hypercortisolism has been associated with the development of several metabolic alterations, mostly caused by the effects of chronic glucocorticoid (GC) exposure over gene expression. The metabolic changes can be partially explained by the GC actions on different adipose tissues (ATs), leadin...

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Bibliographic Details
Main Authors: Flaviane de Fatima Silva, Ayumi Cristina Medeiros Komino, Sandra Andreotti, Gabriela Boltes Reis, Rennan Oliveira Caminhotto, Richardt Gama Landgraf, Gabriel Orefice de Souza, Rogerio Antonio Laurato Sertié, Sheila Collins, Jose Donato, Fabio Bessa Lima
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
Cushing’s syndrome
adipose plasticity
visceral obesity
glucocorticoids
dexamethasone
gene expression
Online Access:https://www.mdpi.com/2227-9059/10/9/2328

Internet

https://www.mdpi.com/2227-9059/10/9/2328

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