Comparative Studies of Vertebrate Beta Integrin Genes and Proteins: Ancient Genes in Vertebrate Evolution

Intregins are heterodimeric α- and β-subunit containing membrane receptor proteins which serve various cell adhesion roles in tissue repair, hemostasis, immune response, embryogenesis and metastasis. At least 18 α- (ITA or ITGA) and 8 β-integrin subunits (ITB or ITGB) are encoded on mammalian genome...

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Bibliographic Details
Main Authors: Ujjwal K. Rout, Roger S. Holmes
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/1/1/3