Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop

Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop

We now know RNA can survive the harsh environment of biofluids when encapsulated in vesicles or by associating with lipoproteins or RNA binding proteins. These extracellular RNA (exRNA) play a role in intercellular signaling, serve as biomarkers of disease, and form the basis of new strategies for d...

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Bibliographic Details
Main Authors: Roger P. Alexander, Robert R Kitchen, Juan Pablo Tosar, Matthew Roth, Pieter Mestdagh, Klaas E. A. Max, Joel Rozowsky, Karolina Elżbieta Kaczor-Urbanowicz, Justin Chang, Leonora Balaj, Bojan Losic, Eric L. Van Nostrand, Emily LaPlante, Bogdan Mateescu, Brian S. White, Rongshan Yu, Aleksander Milosavljevic, Gustavo Stolovitzky, Ryan M. Spengler
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Genetics
Subjects:
extracellular RNA
RNA-seq
RNA sequencing
deconvolulion
batch variation
DREAM challenge
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.778416/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.778416/full

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