Protocol to characterize extracellular c-Src tyrosine kinase function through substrate interaction and phosphorylation
Summary: Cellular Src tyrosine kinase (c-Src) exists in the secretomes of several human cancers (extracellular, e-Src). Phosphoproteomics has demonstrated the existence of 114 potential extracellular e-Src substrates in addition to Tissue Inhibitor of Metalloproteinases 2. Here, we present a protoco...
Main Authors: | Michael P. Omini, Deema Alsalih, SarahBeth D. Votra, Dimitra Bourboulia |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166723007220 |
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