Eukaryotic translation initiation factor 3 subunit B promotes head and neck cancer via CEBPB translation

Eukaryotic translation initiation factor 3 subunit B promotes head and neck cancer via CEBPB translation

Highlights EIF3B is a prognostic biomarker for HNSCC risk; EIF3B promotes HNSCC progression in vitro and in vivo; EIF3B promotes CEBPB translation and activates the MAPK pathway; IL6R and CCNG2 are targets of EIF3B-regulated CEBPB translation.

Bibliographic Details
Main Authors: Chengzhi Xu, Yupeng Shen, Yong Shi, Ming Zhang, Liang Zhou
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Cancer Cell International
Subjects:
Head and neck cancer
Eukaryotic translation initiation factor 3 subunit (B EIF3B)
Translation
CEBPB
IL6R
Online Access:https://doi.org/10.1186/s12935-022-02578-y

Internet

https://doi.org/10.1186/s12935-022-02578-y

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