Clock Protein Bmal1 and Nrf2 Cooperatively Control Aging or Oxidative Response and Redox Homeostasis by Regulating Rhythmic Expression of Prdx6

Many disorders of aging, including blinding-diseases, are associated with deficiency of brain and muscle arnt-like protein 1 (Bmal1) and, thereby, dysregulation of antioxidant-defense pathway. However, knowledge is limited regarding the role of Bmal1 regulation of antioxidant-pathway in the eye lens...

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Bibliographic Details
Main Authors: Bhavana Chhunchha, Eri Kubo, Dhirendra P. Singh
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/8/1861