Immunoglobulin M-degrading enzyme of Streptococcus suis (IdeSsuis) impairs porcine B cell signaling

Immunoglobulin M-degrading enzyme of Streptococcus suis (IdeSsuis) impairs porcine B cell signaling

Streptococcus suis (S. suis) is an important porcine pathogen, causing severe disease like meningitis and septicemia primarily in piglets. Previous work showed that the IgM-degrading enzyme of S. suis (IdeSsuis) specifically cleaves soluble porcine IgM and is involved in complement evasion. The obje...

Full description

Bibliographic Details
Main Authors: Annika Katharina Breitfelder, Wieland Schrödl, Viktoria Rungelrath, Christoph Georg Baums, Gottfried Alber, Nicole Schütze, Uwe Müller
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
Streptococcus suis
IdeSsuis
IgM
B cell receptor
receptor cleavage
B cell signalling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1122808/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1122808/full

Similar Items