A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus

A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus

Leptospirosis is the leading zoonotic disease in terms of morbidity and mortality worldwide. Effective prevention is urgently needed as the drivers of disease transmission continue to intensify. The key challenge has been developing a widely applicable vaccine that protects against the >300 s...

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Bibliographic Details
Main Authors: Elsio A Wunder, Haritha Adhikarla, Camila Hamond, Katharine A Owers Bonner, Li Liang, Camila B Rodrigues, Vimla Bisht, Jarlath E Nally, David P Alt, Mitermayer G Reis, Peter J Diggle, Philip L Felgner, Albert Ko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
leptospira
live attenuated vaccine
leptospirosis
cross-protective immunity
Online Access:https://elifesciences.org/articles/64166

Internet

https://elifesciences.org/articles/64166

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