Potassium Effects on NCC Are Attenuated during Inhibition of Cullin E3–Ubiquitin Ligases
The thiazide-sensitive sodium chloride cotransporter (NCC) plays a vital role in maintaining sodium (Na<sup>+</sup>) and potassium (K<sup>+</sup>) homeostasis. NCC activity is modulated by with-no-lysine kinases 1 and 4 (WNK1 and WNK4), the abundance of which is controlled by...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/1/95 |