Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01
Anti-human leukocyte antigen (HLA) antibodies are important mediators of alloresponses, but structural insights on antibody:HLA interaction are still lacking. Here the authors provide a 2.4 Å structure of antibody:HLA complex, and also analyse HLA features important for other HLA-interacting molecul...
मुख्य लेखकों: | , , , , , , , , , , , , , , , , , |
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स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
Nature Portfolio
2019-02-01
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श्रृंखला: | Nature Communications |
ऑनलाइन पहुंच: | https://doi.org/10.1038/s41467-019-08790-1 |