Metabolic Heterogeneity, Plasticity, and Adaptation to “Glutamine Addiction” in Cancer Cells: The Role of Glutaminase and the GTωA [Glutamine Transaminase—ω-Amidase (Glutaminase II)] Pathway

Many cancers utilize <span style="font-variant: small-caps;">l</span>-glutamine as a major energy source. Often cited in the literature as “<span style="font-variant: small-caps;">l</span>-glutamine addiction”, this well-characterized pathway involves hydr...

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Bibliographic Details
Main Authors: Arthur J. L. Cooper, Thambi Dorai, John T. Pinto, Travis T. Denton
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/8/1131