New perspective on sustained antidepressant effect: focus on neurexins regulating synaptic plasticity

Abstract Depression is highly prevalent globally, however, currently available medications face challenges such as low response rates and short duration of efficacy. Additionally, depression mostly accompany other psychiatric disorders, further progressing to major depressive disorder without long-t...

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Hlavní autoři: Yuan Ruan, Ruolan Yuan, Jiaqi He, Yutong Jiang, Shifeng Chu, Naihong Chen
Médium: Článek
Jazyk:English
Vydáno: Nature Publishing Group 2024-05-01
Edice:Cell Death Discovery
On-line přístup:https://doi.org/10.1038/s41420-024-01974-9