Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects

Endoglin overexpression is associated with highly proliferative tumor endothelium and also with some tumors, including melanoma. Its targeting has anti-tumor effectiveness, which can also be obtained by RNA interference. The aim of our study was to explore the anti-tumor effectiveness of endoglin si...

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Bibliographic Details
Main Authors: Tanja Dolinsek, Gregor Sersa, Lara Prosen, Masa Bosnjak, Monika Stimac, Urska Razborsek, Maja Cemazar
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/8/1/3