Recurrent Acromegaly in a Patient With a CHEK2 Mutation

Recurrent Acromegaly in a Patient With a CHEK2 Mutation

Background/Objective: CHEK2 is a cell-cycle checkpoint kinase and is part of the ATM-CHEK2-p53 cascade, which is protective against carcinogenesis. We describe a germline CHEK2 mutation in a patient with acromegaly and other tumors. Case Report: We present a woman with a germline CHEK2∗ 110delC muta...

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Bibliographic Details
Main Authors: Milica Perosevic, MD, Maria Martinez-Lage, MD, Brooke Swearingen, MD, Nicholas A. Tritos, MD, DSc
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:AACE Clinical Case Reports
Subjects:
acromegaly
CHEK2 gene
pituitary adenoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2376060521001176

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http://www.sciencedirect.com/science/article/pii/S2376060521001176

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