Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome

Vibrio pore-forming leukocidin activates pyroptotic cell death via the NLRP3 inflammasome

ABSTRACTCell death mechanisms are central to combat infections and to drive inflammation. The inflammasome controls infection through activation of caspase-1 leading to either IL-1β dependent inflammation, or pyroptotic cell death in infected cells. Hemolysins, which are pore-forming toxins (PFTs),...

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Bibliographic Details
Main Authors: Hadar Cohen, Noam Baram, Liat Edry-Botzer, Ariel Munitz, Dor Salomon, Motti Gerlic
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Cell death
inflammasome
pyroptosis
IL-1β
Vibrio
leukocidin
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1720526

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2020.1720526

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