The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas

The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas

Metaplastic breast carcinoma (MBC) and uterine carcinosarcoma (UCS) are rare aggressive cancers, characterized by an admixture of adenocarcinoma and areas displaying mesenchymal/sarcomatoid differentiation. We sought to define whether MBCs and UCSs harbor similar patterns of genetic alterations, and...

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Bibliographic Details
Main Authors: Lea A. Moukarzel, Lorenzo Ferrando, Arnaud Da Cruz Paula, David N. Brown, Felipe C. Geyer, Fresia Pareja, Salvatore Piscuoglio, Anastasios D. Papanastasiou, Nicola Fusco, Caterina Marchiò, Nadeem R. Abu‐Rustum, Rajmohan Murali, Edi Brogi, Hannah Y. Wen, Larry Norton, Robert A. Soslow, Anne Vincent‐Salomon, Jorge S. Reis‐Filho, Britta Weigelt
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Molecular Oncology
Subjects:
breast cancer
carcinosarcoma
homologous recombination DNA repair
metaplastic
uterine cancer
whole‐exome sequencing
Online Access:https://doi.org/10.1002/1878-0261.12813

Internet

https://doi.org/10.1002/1878-0261.12813

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