NNNPERFUME: Detection of 8-oxoguanine DNA glycosylase activity based on primer exchange reaction and functionalized hemin/G-quadruplex DNAzyme

Background: 8-oxoguanine DNA glycosylase can maintain genomic stability and integrity. However, it can interfere with the regular DNA damage repair process, possibly leading to the development of cancer and various other human diseases when its activity becomes abnormal. Current methods for detectin...

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Bibliographic Details
Main Authors: Kaiting Xiao, Yanming Lai, Xingxing Liu, Shengjie Li, Wenxu Yuan, Ziyun Wang, Pan Pan, Yongkui Li, Heng Xiao
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Talanta Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266683192400002X