A new computational strategy for identifying essential proteins based on network topological properties and biological information.

Essential proteins are the proteins that are indispensable to the survival and development of an organism. Deleting a single essential protein will cause lethality or infertility. Identifying and analysing essential proteins are key to understanding the molecular mechanisms of living cells. There ar...

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Bibliographic Details
Main Authors: Chao Qin, Yongqi Sun, Yadong Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5533339?pdf=render