The Novel Aminomethylcycline Omadacycline Has High Specificity for the Primary Tetracycline-Binding Site on the Bacterial Ribosome
Omadacycline is an aminomethylcycline antibiotic with potent activity against many Gram-positive and Gram-negative pathogens, including strains carrying the major efflux and ribosome protection resistance determinants. This makes it a promising candidate for therapy of severe infectious diseases. Om...
Main Authors: | Corina G. Heidrich, Sanya Mitova, Andreas Schedlbauer, Sean R. Connell, Paola Fucini, Judith N. Steenbergen, Christian Berens |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
MDPI AG
2016-09-01
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Colecção: | Antibiotics |
Assuntos: | |
Acesso em linha: | http://www.mdpi.com/2079-6382/5/4/32 |
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