HSV-2-Specific Human Female Reproductive Tract Tissue Resident Memory T Cells Recognize Diverse HSV Antigens

HSV-2-Specific Human Female Reproductive Tract Tissue Resident Memory T Cells Recognize Diverse HSV Antigens

Antigen-specific TRM persist and protect against skin or female reproductive tract (FRT) HSV infection. As the pathogenesis of HSV differs between humans and model organisms, we focus on humans with well-characterized recurrent genital HSV-2 infection. Human CD8+ TRM persisting at sites of healed hu...

Full description

Bibliographic Details
Main Authors: David M. Koelle, Lichun Dong, Lichen Jing, Kerry J. Laing, Jia Zhu, Lei Jin, Stacy Selke, Anna Wald, Dana Varon, Meei-Li Huang, Christine Johnston, Lawrence Corey, Christine M. Posavad
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
HSV-2
CD8
CD4
epitope
dendritic cell
female reproductive tract immunology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.867962/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.867962/full

Similar Items