Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during Litomosoides sigmodontis filarial infection

Filarial parasites are tissue dwelling worms transmitted by hematophagous vectors. Understanding the mechanisms regulating microfilariae (the parasite offspring) development is a prerequisite for controlling transmission in filarial infections. Th2 immune responses are key for building efficient ant...

Full description

Bibliographic Details
Main Authors: Estelle Remion, Joséphine Gal, Soraya Chaouch, Jules Rodrigues, Nathaly Lhermitte-Vallarino, Joy Alonso, Linda Kohl, Marc P. Hübner, Frédéric Fercoq, Coralie Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.866373/full