Mendelian Randomization Analysis Provides Insights into the Pathogenesis of Serum Levels of Branched-Chain Amino Acids in Cardiovascular Disease

Mendelian Randomization Analysis Provides Insights into the Pathogenesis of Serum Levels of Branched-Chain Amino Acids in Cardiovascular Disease

Several observational studies have indicated an association between high serum levels of branched-chain amino acids (BCAAs) and an increased risk of cardiovascular disease (CVD). To assess whether theses associations reflect causality, we carried out two-sample Mendelian randomization (MR). Single-n...

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Bibliographic Details
Main Authors: Wenxi Jiang, Ke Lu, Zhenhuang Zhuang, Xue Wang, Xun Tang, Tao Huang, Pei Gao, Yuan Wang, Jie Du
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Metabolites
Subjects:
cardiovascular disease
branched-chain amino acid
mendelian randomization
single-nucleotide polymorphism
neuroendocrine
Online Access:https://www.mdpi.com/2218-1989/13/3/403

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https://www.mdpi.com/2218-1989/13/3/403

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