Evaluation of Spheroid 3D Culture Methods to Study a Pancreatic Neuroendocrine Neoplasm Cell Line

Pancreatic Neuroendocrine Neoplasms (pNEN) are rare tumors which treatment still represent an important clinical problem, due to the paucity of medical treatments. Due to tumor complexity, techniques as 3D cultures are important to study drug activity in a more realistic model. This study aims to co...

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Bibliographic Details
Main Authors: Giulia Bresciani, Leo J. Hofland, Fadime Dogan, Georgios Giamas, Teresa Gagliano, Maria Chiara Zatelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00682/full