Unraveling Molecular Pathways Altered in MeCP2-Related Syndromes, in the Search for New Potential Avenues for Therapy

Unraveling Molecular Pathways Altered in MeCP2-Related Syndromes, in the Search for New Potential Avenues for Therapy

Methyl-CpG-binding protein 2 (MeCP2) is an X-linked epigenetic modulator whose dosage is critical for neural development and function. Loss-of-function mutations in <i>MECP2</i> cause Rett Syndrome (RTT, OMIM #312750) while duplications in the Xq28 locus containing <i>MECP2</i&g...

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Bibliographic Details
Main Authors: Alba-Aina Castells, Rafel Balada, Alba Tristán-Noguero, Mar O’Callaghan, Elisenda Cortès-Saladelafont, Ainhoa Pascual-Alonso, Àngels Garcia-Cazorla, Judith Armstrong, Soledad Alcántara
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomedicines
Subjects:
Rett syndrome
<i>MECP2</i> duplication syndrome
MeCP2
miRNA biomarkers
microcephaly
Online Access:https://www.mdpi.com/2227-9059/9/2/148

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https://www.mdpi.com/2227-9059/9/2/148

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