The evolving role of interferons in viral eradication strategies

Interferons (IFNs) are a family of pleiotropic cytokines that are released when viral infection is sensed by pattern recognition receptors. They induce an antiviral state in target cells through influencing the expression of hundreds of genes termed IFN-stimulated genes (ISGs), which interfere with...

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Bibliographic Details
Main Author: Tomas Doyle
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Virus Eradication
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020304672