An RNAi-based approach to down-regulate a gene family in vivo.

An RNAi-based approach to down-regulate a gene family in vivo.

Genetic redundancy poses a major problem to the analysis of gene function. RNA interference allows the down-regulation of several genes simultaneously, offering the possibility to overcome genetic redundancy, something not easily achieved with traditional genetic approaches. Previously we have used...

Full description

Bibliographic Details
Main Authors: Jeehee Kim, Aurora Badaloni, Torsten Willert, Ursula Zimber-Strobl, Ralf Kühn, Wolfgang Wurst, Matthias Kieslinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827190?pdf=render

Internet

http://europepmc.org/articles/PMC3827190?pdf=render

Similar Items