Multidrug Resistance of Cancer Cells and the Vital Role of P-Glycoprotein

Multidrug Resistance of Cancer Cells and the Vital Role of P-Glycoprotein

P-glycoprotein (P-gp) is a major factor in the multidrug resistance phenotype in cancer cells. P-gp is a protein that regulates the ATP-dependent efflux of a wide range of anticancer medicines and confers resistance. Due to its wide specificity, several attempts have been made to block the action of...

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Bibliographic Details
Main Authors: Chenmala Karthika, Raman Sureshkumar, Mehrukh Zehravi, Rokeya Akter, Faraat Ali, Sarker Ramproshad, Banani Mondal, Priti Tagde, Zubair Ahmed, Farhat S. Khan, Md. Habibur Rahman, Simona Cavalu
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Life
Subjects:
multidrug resistance
P-gp
cancer
inhibitors
clinical trials
Online Access:https://www.mdpi.com/2075-1729/12/6/897

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https://www.mdpi.com/2075-1729/12/6/897

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