Evolution and Functional Diversification of the GLI Family of Transcription Factors in Vertebrates

Background: In vertebrates the “SONIC HEDGEHOG” signalling pathway has been implicated in cell-fate determination, proliferation and the patterning of many different cell types and organs. As the GLI family members (GLI1, GLI2 and GLI3) are key mediators of hedgehog morphogenetic signals, over the...

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Bibliographic Details
Main Authors: Amir Ali Abbasi, Debbie K. Goode, Saneela Amir, Karl-Heinz Grzeschik
Format: Article
Language:English
Published: SAGE Publishing 2009-01-01
Series:Evolutionary Bioinformatics
Subjects:
Online Access:http://www.la-press.com/evolution-and-functional-diversification-of-the-gli-family-of-transcri-a1468