The Role of Knockout Olfactory Receptor Genes in Odor Discrimination

The Role of Knockout Olfactory Receptor Genes in Odor Discrimination

To date, little is known about the role of olfactory receptor (OR) genes on smell performance. Thanks to the availability of whole-genome sequencing data of 802 samples, we identified 41 knockout (KO) OR genes (i.e., carriers of Loss of Function variants) and evaluated their effect on odor discrimin...

Full description

Bibliographic Details
Main Authors: Maria Pina Concas, Massimiliano Cocca, Margherita Francescatto, Thomas Battistuzzi, Beatrice Spedicati, Agnese Feresin, Anna Morgan, Paolo Gasparini, Giorgia Girotto
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Genes
Subjects:
whole-genome sequencing
odor discrimination
olfactory receptors genes
loss of function variants
human knockouts
gene expression
Online Access:https://www.mdpi.com/2073-4425/12/5/631

Internet

https://www.mdpi.com/2073-4425/12/5/631

Similar Items