Pulsed Nanoelectrospray Ionization Boosts Ion Signal in Whole Protein Mass Spectrometry

Pulsed Nanoelectrospray Ionization Boosts Ion Signal in Whole Protein Mass Spectrometry

Electrospray ionisation (ESI) is renowned for its ability to ionise intact proteins for sensitive detection by mass spectrometry (MS). However, the use of a conventional direct current ESI voltage can result in the formation of relatively large initial droplet sizes, which can limit efficient ion de...

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Bibliographic Details
Main Authors: Qinwen Liu, Ezaz Ahmed, K. M. Mohibul Kabir, Xiaojing Huang, Dan Xiao, John Fletcher, William A. Donald
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Applied Sciences
Subjects:
electrospray ionisation
nanoelectrospray
proteins
alternating current
top-down
Online Access:https://www.mdpi.com/2076-3417/11/22/10883

Internet

https://www.mdpi.com/2076-3417/11/22/10883

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