Omega-Class Glutathione Transferases of Carcinogenic Liver Fluke, <i>Clonorchis sinensis</i>, Modulate Apoptosis and Differentiation of Host Cholangiocytes

Omega-Class Glutathione Transferases of Carcinogenic Liver Fluke, <i>Clonorchis sinensis</i>, Modulate Apoptosis and Differentiation of Host Cholangiocytes

The small liver fluke <i>Clonorchis sinensis</i> causes hepatobiliary ductal infections in humans. Clonorchiasis is characterized histopathologically by ductal dysplasia, hyperplasia and metaplasia, which closely resembles cholangiocarcinoma (CCA). The disruption of programmed cell death...

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Bibliographic Details
Main Authors: Chun-Seob Ahn, Jeong-Geun Kim, Insug Kang, Yoon Kong
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Antioxidants
Subjects:
<i>Clonorchis sinensis</i>
omega-class glutathione transferase
cholangiocyte
oxidative stress
programmed cell death
cell differentiation
Online Access:https://www.mdpi.com/2076-3921/10/7/1017

Internet

https://www.mdpi.com/2076-3921/10/7/1017

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