Structure–Activity Relationship of Novel ACE Inhibitory Undecapeptides from <i>Stropharia rugosoannulata</i> by Molecular Interactions and Activity Analyses

Structure–Activity Relationship of Novel ACE Inhibitory Undecapeptides from <i>Stropharia rugosoannulata</i> by Molecular Interactions and Activity Analyses

Undecapeptide is the central peptide molecule in the peptide base material of <i>Stropharia rugosoannulata</i>, and angiotensin-converting enzyme (ACE) plays a crucial role in hypertension. To fully explore the interaction mechanism and ACE-inhibitory activity of long-chain peptides from...

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Bibliographic Details
Main Authors: Wen Li, Wanchao Chen, Jinbin Wang, Zhengpeng Li, Zhong Zhang, Di Wu, Mengqiu Yan, Haile Ma, Yan Yang
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Foods
Subjects:
<i>Stropharia rugosoannulata</i> undecapeptides
molecular docking
molecular dynamics simulation
molecular thermodynamics reaction
molecular dynamics reaction
ACE inhibition mechanism
Online Access:https://www.mdpi.com/2304-8158/12/18/3461

Internet

https://www.mdpi.com/2304-8158/12/18/3461

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