The Protective Effect of Polygonum cuspidatum (PCE) Aqueous Extract in a Dry Eye Model

The Protective Effect of Polygonum cuspidatum (PCE) Aqueous Extract in a Dry Eye Model

Dry eyes are caused by highly increased osmolarity of tear film, inflammation, and apoptosis of the ocular surface. In this study, we investigated the effect of Polygonum cuspidatum (PCE) aqueous extract in in vivo and in vitro dry eye models. Dry eye was induced by excision of the lacrimal gland an...

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Bibliographic Details
Main Authors: Bongkyun Park, Ik Soo Lee, Soo-Wang Hyun, Kyuhyung Jo, Tae Gu Lee, Jin Sook Kim, Chan-Sik Kim
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Nutrients
Subjects:
Polygonum cuspidatum
hyperosmolar stress
exorbital lacrimal gland-excised
dry eye
human corneal epithelial cells
inflammation
apoptosis
oxidative stress
matrix metallopeptidase 9 (MMP9)
Mucin4
Online Access:http://www.mdpi.com/2072-6643/10/10/1550

Internet

http://www.mdpi.com/2072-6643/10/10/1550

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