Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma

Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma

B lymphocytes are important players in immune responses to cancer. However, their composition and function in head and neck squamous cell carcinoma (HNSCC) has not been well described. Here, we analyzed B cell subsets in HNSCC (n = 38), non-cancerous mucosa (n = 14) and peripheral blood from HNSCC p...

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Bibliographic Details
Main Authors: Axel Lechner, Hans A. Schlößer, Martin Thelen, Kerstin Wennhold, Sacha I. Rothschild, Ramona Gilles, Alexander Quaas, Oliver G. Siefer, Christian U. Huebbers, Engin Cukuroglu, Jonathan Göke, Axel Hillmer, Birgit Gathof, Moritz F. Meyer, Jens P. Klussmann, Alexander Shimabukuro-Vornhagen, Sebastian Theurich, Dirk Beutner, Michael von Bergwelt-Baildon
Format: Article
Language:English
Published: Taylor & Francis Group 2019-03-01
Series:OncoImmunology
Subjects:
head and neck squamous cell carcinoma
b cells
humoral immune response
tumor-associated antigens
tumor microenvironment
tertiary lymphoid structures
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1535293

Internet

http://dx.doi.org/10.1080/2162402X.2018.1535293

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