Early separation and parallel clonal selection of dedifferentiated and well-differentiated components in dedifferentiated liposarcoma

Early separation and parallel clonal selection of dedifferentiated and well-differentiated components in dedifferentiated liposarcoma

Dedifferentiated liposarcoma (DDLPS) comprises a high-grade dedifferentiated (DD) component and a juxtaposed well-differentiated (WD) component. The DD component is believed to originate from the WD component by acquiring additional genomic alterations. In this study, we performed multiregion genome...

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Bibliographic Details
Main Authors: Tetsuya Sekita, Naofumi Asano, Takashi Kubo, Hirohiko Totsuka, Sachiyo Mitani, Naoko Hattori, Akihiko Yoshida, Eisuke Kobayashi, Motokiyo Komiyama, Toshikazu Ushijima, Robert Nakayama, Masaya Nakamura, Akira Kawai, Hitoshi Ichikawa
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
DDLPS
Dedifferentiation
Clonal evolution
Multiregion analysis
Phylogenetic tree
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558624001155

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http://www.sciencedirect.com/science/article/pii/S1476558624001155

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