Exploring the role of L209 residue in the active site of NDM-1 a metallo-β-lactamase.

New Delhi Metallo-β-Lactamase (NDM-1) is one of the most recent additions to the β-lactamases family. Since its discovery in 2009, NDM-1 producing Enterobacteriaceae have disseminated globally. With few effective antibiotics against NDM-1 producers, there is an urgent need to design new drug inhibit...

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Bibliographic Details
Main Authors: Francesca Marcoccia, Hanna-Kirsti S Leiros, Massimiliano Aschi, Gianfranco Amicosante, Mariagrazia Perilli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5749715?pdf=render