Intracellular niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of Salmonella enterica.

Salmonella enterica serovar Typhimurium (S. Typhimurium) is a zoonotic pathogen that causes diarrheal disease in humans and animals. During salmonellosis, S. Typhimurium colonizes epithelial cells lining the gastrointestinal tract. S. Typhimurium has an unusual lifestyle in epithelial cells that beg...

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Main Authors: TuShun R Powers, Amanda L Haeberle, Alexander V Predeus, Disa L Hammarlöf, Jennifer A Cundiff, Zeus Saldaña-Ahuactzi, Karsten Hokamp, Jay C D Hinton, Leigh A Knodler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009280