Marked differences in tight junction composition and macromolecular permeability among different intestinal cell types

Marked differences in tight junction composition and macromolecular permeability among different intestinal cell types

Abstract Background Mammalian small intestinal tight junctions (TJ) link epithelial cells to one another and function as a permselective barrier, strictly modulating the passage of ions and macromolecules through the pore and leak pathways, respectively, thereby preventing the absorption of harmful...

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Bibliographic Details
Main Authors: Sarah C. Pearce, Arwa Al-Jawadi, Kunihiro Kishida, Shiyan Yu, Madeleine Hu, Luke F. Fritzky, Karen L. Edelblum, Nan Gao, Ronaldo P. Ferraris
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Biology
Subjects:
Claudin
Differentiation
Enterocyte
Epithelia
Leak pathway
Paracellular
Online Access:http://link.springer.com/article/10.1186/s12915-018-0481-z

Internet

http://link.springer.com/article/10.1186/s12915-018-0481-z

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