Small colony variants and single nucleotide variations in Pf1 region of PB1 phage-resistant Pseudomonas aeruginosa

Small colony variants and single nucleotide variations in Pf1 region of PB1 phage-resistant Pseudomonas aeruginosa

Phage therapy involves the application of lytic bacteriophages for treatment of clinical infections but bacterial resistance may develop over time. Isolated from nosocomial infections, small colony variants (SCVs) are morphologically distinct, highly virulent bacterial strains that are resistant to...

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Bibliographic Details
Main Authors: Wee Siang eLim, Kevin Kai Siang ePhang, Andy Hee-Meng eTan, Sam Fong-Yau eLi, Dave Siak-Wei eOw
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Microbiology
Subjects:
Pseudomonas aeruginosa
phage therapy
small colony variants
phage resistance
lipopolysaccharide (LPS)
Pf1 region
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00282/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00282/full

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